43546 Multiple programs crash with unimplemented function vcomp{100,110,140}.dll._vcomp_for_static_simple_init_i8 (Astrotoaster, Gaea-1.0.16.8020, easyHDR 3.13.0, SimIon, BlueSkyPlan)
44055 Multiple applications fail to run in Win7+ mode, requiring DWM composition API support to be enabled (Aero Glass, transparent windows)(Affinity Designer 1.x, Electron-based apps using isAeroGlassEnabled API)
50088 Memento Mori needs WMReaderAdvanced2_OpenStream
51267 Rise of Legends Demo crashes with null pointer exception inside SAXReader::parseURL
51628 Samsung SDK 1.2.2 for Java ME: Black window
51677 Resident Evil 4 HD crashes when gameplay starts
51684 quartz:systemclock gets out of order timestamps on Windows
51719 _pclose() does not cause child stdin to report EOF
51815 DocumentProperties broken by last update (x64 only)
51851 Resident Evil 6 stops to a black screen instead of playing videos (needs WMSyncReader_GetOutputCount)
51856 access violation at emfdc_delete_object+0x17
51911 vbscript does not handle strings in if clauses
51914 Color picker doesn't render with custom themes
51917 Internet Explorer 8 crashes when visiting http://www.baidu.com/ on unimplemented function dxtrans.dll.DllGetClassObject
51919 New sal.h macros break libstdc++ includes in wineg++
51921 Multiple games crash due to assertion failures in bundled FAudio (Unreal Engine 4 games, Skyrim SE)
51926 Wine fails to build with glibc headers < 2.24
51937 Resident Evil 6 stops to a black screen instead of playing videos (needs WMSyncReader_GetOutputProps)
51951 configure says that libsane development files are not found even though they are present
Bugs fixed in 6.22 (total 29):
21572 KFSensor 4.x/5.x: 'kfsnserv.exe' service fails to reliably stop/start/restart
22260 Total Commander 7.x/8.x: editable dropdown is gray when opened and empty
30498 Shadows broken on many games because of wrong depth formats
38278 Multiple apps and games need wmvcore.dll.WMReader_Open implementation (Nail'd demo)
42030 winedbg: Internal crash at 0x9f58fd40
45130 Builtin xaudio2_7.dll break audio and slow down performance for some games since wine 3.5
45443 Diablo 3: Starting the game causes a black screen softlock on the X-environment
46512 Window text has last letter cut off
47119 winedbg truncates 64-bit address when compiled with mingw
49409 Monkey Island 2 Special Edition crash / freeze with built-in xactengine3_6
49803 WIDL cannot import TLBs stored as resources in PE, such as stdole32.tlb and stdole2.tlb (even though both have tlb extension, they are essentially PE)
50292 Process-local synchronization objects use private interfaces into the Unix library
50757 (Regression) Hyperdimension Neptunia Re;Birth1 Crashes/freezes frequently with FAudio
51027 Fonts blurred for some words in Logos Bible Software
51587 Force feedback strength is really low in multiple games
51864 VeraCrypt Installer for 1.24-Update7 (Win8+) fails with HRESULT 0x800288BD
51916 Empire Earth 2 UP 1.5: ImageButtons don't render right with custom themes
51938 Safe Exam Browser needs "DNSDomain" from Win32_NetworkAdapterConfiguration
51944 Resident Evil 6 stops to a black screen instead of playing videos
51953 Joystick not detected for some older games with wine 6.20
51956 Morrowind: freezes when control keys are changing
51968 Winaero WEI Tool: Crash due to C:\windows\performance\winsat\datastore missing
51970 Memento Mori needs output_props_GetType
51978 Autodesk Fusion 360 crashes on unimplemented function msvcp140.dll.?table@?$ctype@D@std@@QEBAPEBFXZ
51983 foobar2000 v1.5.1+ crashes on startup with Wine v6.6+ with Windows version set to "Windows 10"
52022 Multiple games have unresponsive mouse/keyboard (Borderlands GOTY Enhanced, Tom Clancy's Rainbow Six Siege, Resident Evil Revelations)
52044 Safe exambrowser needs msctfmonitor.dll
52051 Oceanhorn: Monster of Uncharted Seas fails to start (uses WINED3DFMT_R8G8_UINT in vertex declaration)
52052 Wine doesn't show any window while creating/updating 64-bit prefix